Refractory ulcerative colitis complicated by cytomegalovirus infection successfully treated with valganciclovir

Refractory ulcerative colitis complicated by cytomegalovirus infection successfully treated with valganciclovir

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Cytomegalovirus (CMV) infection is widespread in the general population.In patients with severe and/or steroid-refractory ulcerative colitis (UC), local reactivation of CMV can be swisse high strength magnesium powder berry detected in actively inflamed colonic tissue in approximately 30% of cases.However, the role of CMV in patients with UC is not clearly understood.There is evidence to show a possible role in exacerbating a colitis flare, whereas other studies describe CMV as an innocent bystander.We report the case of a patient with 730 sunken lake road severe UC complicated by CMV infection who did not respond to conventional therapy.

A complete diagnostic panel for CMV diagnosis, including tissue polymerase chain reaction and immunohistochemistry, was carried out.Three-week therapy with oral valganciclovir resulted in dramatic clinical and endoscopic improvement.Timing of diagnosis and treatment of CMV infection complicating UC is crucial in order to recognize the organ-disease and plan appropriate treatment.